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CEBPB — LPA

Text-mined interactions from Literome

He et al., Biochem J 2008 : Downregulation of EGFR by siRNA or pretreatment with the EGFR tyrosine kinase inhibitor, AG1478, partly attenuated LPA induced COX-2 expression and phosphorylation of C/EBPbeta ; however, neither of these factors had an effect on the NF-kappaB and JNK pathways ... These results demonstrate that LPA induces COX-2 expression and PGE ( 2 ) production through EGFR transactivation independent activation of transcriptional factors NF-kappaB and c-Jun, and EGFR transactivation dependent activation of C/EBPbeta in HBEpCs
Oyesanya et al., FASEB J 2008 (Ovarian Neoplasms) : Furthermore, LPA stimulated C/EBPbeta phosphorylation and activity through a novel mechanism integrating GPCR signals and a permissive activity from a receptor tyrosine kinase ( RTK )