Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
MAPK8
→
TNFRSF17
(increases, TNFRSF17 Activity, MAPK8 Activity)
Evidence: The protein encoded by this gene (TNFRSF17)is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals f...