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CD79A — IL4

Text-mined interactions from Literome

Goodrich et al., Immunol Invest 1999 : However, neither IL-4 , IL- 5, nor IFN-gamma affected IgA secretion with the IEC-SN
Krzysiek et al., J Immunol 1999 : We show herein that B cell Ag receptor (BCR) triggering, but not stimulation by CD40 mAb and/or IL-4 , rapidly induced the coordinated expression of two closely related T cell chemoattractants, macrophage inflammatory protein-1 beta ( MIP-1 beta ) and MIP-1 alpha, by human B cells
Wu et al., Ann Surg 1999 : To examine the levels of a Th1 IgA inhibiting cytokine ( interferon gamma ) and the Th2 IgA stimulating cytokines ( interleukin [IL]-4 , IL-5, IL-6, and IL-10 ) within the intestine of animals manipulated with enteral or parenteral nutrition, and to correlate these cytokine alterations with intestinal IgA levels ... The IgA stimulating cytokine IL-4 drops significantly in mice receiving IG and IV TPN in association with reduced IgA levels, whereas IL-10 decreases significantly only in mice receiving IV TPN
Nies et al., J Investig Allergol Clin Immunol 2002 (Respiratory Hypersensitivity) : Suppression of IgA- , IgG, and IgM- synthesis was induced by stimulation of B cells with IL-4
van Vlasselaer et al., J Immunol 1992 : Interestingly, IL-4 specifically blocked IgA production in this culture system, indicating that IL-4 inhibits only antibody production by IgA committed B cells
Asano et al., Clin Exp Immunol 2004 (IgA Deficiency) : In some patients, IgA secretion was induced by stimulation with anti-CD40, IL-4 and IL-10
Rao et al., Int Immunol 1992 (Lymphoma, B-Cell) : Neither their IgA nor their IgG receptor expression is affected by IL-4 or by IFNs-alpha, -beta, or -gamma
Matsumoto et al., Immunology 1989 : Polyclonal IgA secretion of lipopolysaccharide stimulated normal B cells was augmented preferentially by IL-5, but not by IL-4
Yano et al., Clin Exp Immunol 1992 (Glomerulonephritis, IGA) : In order to elucidate the factors responsible for altered immunoglobulin production in patients with IgA nephropathy (IgAN), the in vitro effects of IL-4 and interferon-gamma (IFN-gamma) on the synthesis of IgE and IgA by peripheral blood mononuclear cells ( PBMC ) were studied ... The enhancement rate of IL-4 induced IgE and IgA synthesis was significantly lower in IgAN than in the controls, suggesting in vivo preactivation of PBMC in IgAN patients
Giri et al., FEMS Immunol Med Microbiol 2005 (Disease Models, Animal...) : Vaccination via intranasal and subcutaneous routes triggered immune activation in the spleen and cervical lymph node, while the former route of vaccination lead to higher antigen-specific lymphocyte proliferation, interferon-gamma, interleukin-12 and interleukin-4 responses in cervical lymph node and induction of antigen-specific IgA responses at mucosal level of the respiratory tract
Vallé et al., Int Immunol 1991 : SAC stimulated B7+ B cells proliferated and produced IgM, IgG and IgA in response to IL-2 and IgM and IgG in response to IL-4
Croft et al., J Immunol 1991 : IL-4 was required for optimal IgM, IgG1, and IgA secretion, but limited secretion of IgG2a, whereas IFN-gamma was required for optimal IgG2a secretion, and limited IgM, IgG1, and IgA
Nguyen et al., Vet Immunol Immunopathol 2007 : Interleukin-4 induced inverse dose dependent ( 0.1 ng > 10 ng/ml ) isotype switching to IgA and enhanced IgM secreting cell responses to LPS and rotavirus
Neuber et al., Immunology 1991 (Dermatitis, Atopic) : Additional stimulation with interleukin-4 (IL-4) also led to a pronounced suppression of the IgE and IgA synthesis in normal donor cells, while the effect of S. aureus on PBL of atopic donors was not markedly affected by IL-4
Borte et al., Klin Padiatr 2010 (Common Variable Immunodeficiency) : Stimulation with IL-21, IL-4 and CD40L uniformly induced IgG and IgA production in B cells from all tested patients by initiation of both CSR and AID independent Ig production
Phillips et al., J Immunol 1990 : Synergistic effect of IL-4 and IFN-gamma on the expression of polymeric Ig receptor ( secretory component ) and IgA binding by human epithelial cells
de Andrés et al., J Immunol 2012 : Moreover, in vitro stimulation of splenic 19?45R ( lo ) cells with LPS, CpG, BAFF/IL4 , and CD40/IL4 induced cell proliferation, IgG1/IgA secretion and the release of IL-10, suggesting a potential immunoregulatory role for this subset of innate-like B cells
Maiolini et al., BMC veterinary research 2013 (Arteritis...) : To investigate if transforming growth factor beta 1 ( TGF-ß1 ), interleukin-6 (IL-6) and vascular endothelial growth factor ( VEGF ) are involved in the production of excessive immunoglobulin A (IgA) , the induction of acute phase proteins and in the development of a systemic necrotizing vasculitis, characteristic of SRMA, these three signalling proteins were evaluated
Thyphronitis et al., Proc Natl Acad Sci U S A 1989 (Cell Transformation, Viral) : While IL-4 also enhanced IgM, IgG, and IgA secretion, as well as proliferation by EBV infected B cells, these effects were less pronounced, occurred earlier during culture, and required a lower concentration of IL-4 than did the stimulation of IgE secretion
Pène et al., Proc Natl Acad Sci U S A 1988 : In addition, a low induction of IgG production was observed, whereas IL-4 had no effect on IgA and IgM synthesis
Pène et al., Eur J Immunol 1988 : In contrast, IL 4 ( 50 U/ml ) blocked IL 5-induced IgA synthesis
Lebman et al., J Immunol 1988 : The effects of IL-4 and IL-5 on the IgA response by murine Peyer 's patch B cell subpopulations ... Maximum enhancement of IgA in such cultures, however, requires IL-4 in addition to IL-5
Lim et al., Biosci Biotechnol Biochem 1995 : In the absence of lipopolysaccharide (LPS), IL-4 enhanced the IgE and IgG production significantly and the IgA production weakly, but not the IgM production
Haq et al., Reg Immunol 1993 : Both anti-IL-4 and anti-IL-5 Mabs blocked the respective IL-4 and IL-5 induced enhancement of antigen-specific IgG or IgA antibody production
Kimata et al., Biotechnol Ther 1993 : Of various cytokines tested, including IFN-alpha, IFN-gamma, IL-1 beta, IL-2, IL-3, IL-4 , IL-5, and IL-6, IL-6 alone augmented IgG2 induced enhancement of IgA production and proliferation
Kotowicz et al., Eur J Immunol 1993 : In some experiments, however, IL-4 enhanced IgM secretion by sIgM+ B cells, and IgA , IgG1, IgG2, IgG3 by sIgM- B cells, suggesting that it may have an additional B cell differentiation factor activity which was not isotype specific
Brodie et al., Eur J Immunol 1996 : Antagonistic effects of NGF and IL-4 were also observed for other Ig isotypes since IL-4 prevented the increase in IgA and IgM production induced by NGF
Yamamoto et al., Ann N Y Acad Sci 1996 : Further, lack of IL-4 results in failure to induce mucosal IgA responses
Denning et al., J Immunol 1996 : IL-4 and IFN-gamma synergistically increase total polymeric IgA receptor levels in human intestinal epithelial cells
Yano et al., Nephron 1996 (Glomerulonephritis...) : It is concluded that IL-4 and sCD23 might play decisive roles in in vitro and in vivo hyperproduction of IgA and IgE in patients with IgAN, and that sCD23 seemed to control IgE but not IgA synthesis through a unique pathway
Chintalacharuvu et al., J Immunol 1997 (Lymphoma, B-Cell) : These results suggest that the increased production of IL-4 and IL-5 by peripheral blood lymphocytes from IgA nephropathy patients might result in the production of abnormally glycosylated IgA
Marconi et al., Clin Exp Immunol 1998 (IgA Deficiency) : The most striking finding of this study was the synergizing effect of IL-4 on IgA production in the IgAD group when added with IL-10 ; median IgA supernatant level increased to a value superimposable on that found in the normal controls which remained about the same as when stimulated with IL-10 alone