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EPHB2 — TREM2

Text-mined interactions from Literome

Bouchon et al., J Immunol 2000 (Calcium Signaling...) : Intracellularly, TREM-1 induces Ca2+ mobilization and tyrosine phosphorylation of extracellular signal related kinase 1 ( ERK1 ), ERK2 and phospholipase C-gamma
Peng et al., Science signaling 2010 : Here, we demonstrate that the ligation of TREM2 activated phosphatidylinositol 3-kinase (PI3K), extracellular signal regulated kinase 1 ( ERK1 ) and ERK2 , and the guanine nucleotide exchange factor Vav3 ; induced the mobilization of intracellular calcium ( Ca ( 2+ ) ) and the reorganization of actin ; and prevented apoptosis