Gene interactions and pathways from curated databases and text-mining

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BDKRB2 — EPHB2

Text-mined interactions from Literome

Barki-Harrington et al., Biochem J 2003 (Bone Neoplasms...) : Specific stimulation of either B1R or B2R by their respective agonists des-Arg ( 9 ) -BK and Lys-BK promoted ERK activation and cell growth, whereas selective blockade with specific antagonists des-Arg ( 9 ) - [ Leu ( 8 ) ] BK and Hoe 140 respectively obliterated this effect, indicating the presence of both receptor subtypes ... However, blockade of B1R also inhibited B2R mediated ERK activation and cell growth, and, similarly, antagonism of B2R inhibited the B1R mediated response
Fields et al., Journal of neuroinflammation 2012 (Inflammation) : Inhibiting extracellular regulated kinase (ERK)1/2 activation blocked IL-1ß induced BDKRB2 mRNA expression while increasing COX-2 expression