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BDKRB2 — EPHB2
Text-mined interactions from Literome
Barki-Harrington et al., Biochem J 2003
(Bone Neoplasms...) :
Specific stimulation of either B1R or
B2R by their respective agonists des-Arg ( 9 ) -BK and Lys-BK
promoted ERK activation and cell growth, whereas selective blockade with specific antagonists des-Arg ( 9 ) - [ Leu ( 8 ) ] BK and Hoe 140 respectively obliterated this effect, indicating the presence of both receptor subtypes ... However, blockade of B1R also inhibited
B2R mediated
ERK activation and cell growth, and, similarly, antagonism of B2R inhibited the B1R mediated response
Fields et al., Journal of neuroinflammation 2012
(Inflammation) :
Inhibiting
extracellular regulated kinase (ERK)1/2 activation
blocked IL-1ß induced
BDKRB2 mRNA expression while increasing COX-2 expression