Gene interactions and pathways from curated databases and text-mining

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IL2RG — TNF

Text-mined interactions from Literome

Muñoz-Fernández et al., Eur J Immunol 1990 : More interestingly, TNF significantly increased the number of high-affinity IL2R on purified T cells in the presence of phorbol 12,13-dibutyrate
Panzer et al., Clin Exp Immunol 1993 : We show in this system that exogenously added IL-1 beta, IL-6 and TNF-alpha induces IL-2 receptor (R) up-regulation and IL-2 production, and proliferation by both CD4+ and CD8+ cells
Sumiyoshi et al., J Gastroenterol 1997 (Pancreatic Neoplasms) : The secretion of C4 and factor B in ductal cell lines ( PANC-1 and MIA PaCa-2 ) was independently regulated by interleukin (IL)-1 beta, tumor necrosis factor (TNF)-alpha, and interferon (IFN)-gamma ; C4 secretion was induced by IFN-gamma, whereas factor B secretion was induced by IL-1 beta, TNF-alpha , or IFN-gamma
Bonder et al., J Immunol 1998 : Studies with Abs to gammac and an IL-4 mutant that is unable to bind to gammac showed that IL-4 can suppress IL-1beta but not TNF-alpha production by LPS stimulated monocytes in the presence of little or no functioning gammac