Gene interactions and pathways from curated databases and text-mining

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ACSL3 — OSM

Text-mined interactions from Literome

Zhou et al., Arterioscler Thromb Vasc Biol 2007 (Disease Models, Animal...) : Transcriptional activation of hepatic ACSL3 and ACSL5 by oncostatin m reduces hypertriglyceridemia through enhanced beta-oxidation
Cao et al., J Biol Chem 2010 (Carcinoma, Hepatocellular...) : Our previous studies showed that ACSL3 was transcriptionally up-regulated by the cytokine oncostatin M (OSM) in HepG2 cells, accompanied by reduced cellular triglyceride content and enhanced beta-oxidation ... In this study, we investigated the molecular mechanism underlying the OSM induced activation of ACSL3 gene transcription in HepG2 cells ... The effect of OSM on ACSL3 mRNA expression was inhibited by cellular depletion of PPARdelta