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IL10 — MSC

Text-mined interactions from Literome

Zheng et al., Rheumatology (Oxford) 2008 (Arthritis, Rheumatoid) : The effects of both MSCs and MSC-chondrocytes on the proliferation, activation-antigen expression ( CD69 and CD25 ) and cytokine production [interferon-gamma ( IFN-gamma ), tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-10 and IL-4 ] of CII-reactive T cells in RA patients were investigated with the stimulation of CII or otherwise
Sundin et al., J Immunother 2009 (Graft vs Host Disease) : Although MSC up-regulated lymphocyte gene expression of CD25, IFN-gamma, FoxP3, CTLA-4, and IL-10 , they failed in both unprimed and primed responders to induce CD25+ ( activated ) or CD57+ ( effector ) CD4+ or CD8+ T-lymphocyte subsets and only inconsistently induced FoxP3+ regulatory T-lymphocytes
Hsu et al., J Immunol 2013 (Arteriosclerosis) : In an MLR system using porcine PBMCs, MSC induced IL-10 ( + ) IFN-? ( + ) CD4 ( + ) cells, which confer resistance to allogeneic proliferation in an IL-10 dependent manner, resemble T(R)1-like cells ... These findings indicate that PGE ( 2 ) helps MSC induced IL-10 ( + ) IFN-? ( + ) CD4 ( + ) T(R)1-like cells inhibit TA
Chai et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2013 : ( 4 ) The serum IL-10 level significantly increased in the OM therapy group, the MSC therapy group, and the MSC combined OM therapy group ( P < 0.05 ), and it was the highest in the MSC combined OM therapy group among the three groups ( P < 0.05 )