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WNT2 — WNT3
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Le Floch et al., FASEB J 2005
(Colonic Neoplasms...) :
Upstream
activation of
Wnt signaling by the Wnt-2 and Wnt-3a ligands, stable overexpression of
Wnt-2 , as well as GSK-3beta inhibition by lithium, SB216763, and GSK-3beta dominant negative forms ( K85R and R96E ) conferred the invasive phenotype through several proinvasive pathways
Chiba et al., Exp Hematol 2004
:
In contrast, gene transfer of
Wnt3 into both hTERT-stromal cells and hTERT-MSCs
enhanced Wnt-betacatenin signaling, and caused remarkable morphological changes and growth retardation
Shi et al., Int J Cancer 2007
(Colorectal Neoplasms) :
In this study, we investigated
roles of
Wnt-2 and Gal-3 in the regulation of canonical
Wnt/beta-catenin signaling
Bayle et al., J Invest Dermatol 2008
(Scleroderma, Systemic) :
Increased expression of
Wnt2 and SFRP4 in Tsk mouse skin :
role of
Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis