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Li et al., Science 2000
:
Dominant negative Rac inhibited IFN-gamma production in murine T cells ... Thus, Rac2 activates TH1-specific signaling and IFN-gamma gene expression
Croker et al., Immunol Cell Biol 2002
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To investigate the requirement for Rac2 in IFN-gamma production and TH1 responses in vivo, Rac2-deficient mice were challenged with Leishmania major and immunized with ovalbumin expressing cytomegalovirus