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DEFB103B — IFNG

Text-mined interactions from Literome

Nomura et al., J Immunol 2003 (Dermatitis, Atopic...) : We found that IL-13 and IL-4 inhibited TNF-alpha- and IFN-gamma induced HBD-3 production
Fahlgren et al., Clin Exp Immunol 2004 (Colitis, Ulcerative...) : Interferon (IFN)-gamma , but not tumour necrosis factor (TNF)-alpha or IL-1beta, augmented hBD-3 mRNA expression
Joly et al., Mol Immunol 2005 : An inhibitor of JAK2 kinase ( Janus kinase ), down-regulated IFN-gamma induced HBD-1 and HBD-3 expression, suggesting a role for the JAK/signal transducer and activator of transcription ( STAT ) signaling pathway in their expression
Albanesi et al., J Immunol 2007 : We demonstrate here that stimulation of keratinocytes with TNF-alpha/IFN-gamma induces HBD-2 and HBD-3 by activating STAT-1 and NF-kappaB signaling ... This interferes with STAT-1 and NF-kappaB signaling, thereby inhibiting TNF-alpha/IFN-gamma mediated induction of HBD-2 and HBD-3