◀ Back to ATR

ATR — CYP19A1

Text-mined interactions from Literome

Heneweer et al., Toxicol Lett 2004 (Adrenal Cortex Neoplasms...) : However, ATR did not induce aromatase activity in R2C cells
Holloway et al., J Appl Toxicol 2008 : Thus, it is suggested that ATR can increase local tissue estrogen levels in estrogen sensitive target tissues through increased aromatase activity ... Therefore the effect of ATR on aromatase activity was measured in human granulosa-lutein cell cultures, cells that abundantly express aromatase, and endometrial stromal cell ( ESC ) cultures, cells that do not express aromatase ... There were no treatment related changes in cellular protein and thus it is suggested that the ATR induced change in aromatase activity was not due to an increase in cell number