Gene interactions and pathways from curated databases and text-mining

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BCAR1 — MAPK3

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: MAPK3 → BCAR1 (increases, BCAR1 Activity) Cabodi et al., J Cell Sci 2004
    Evidence: We show that in the human breast carcinoma T47D cells, upon estrogen treatment, p130Cas rapidly and transiently associates with the estrogen receptor alpha in a multi-molecular complex containing the c-Src kinase and the p85 subunit of PI 3-kinase. Association of p130Cas with the estrogen receptor alpha occurs within 3 minutes of estrogen treatment and is dependent on c-Src kinase activation. Transient overexpression of p130Cas in T47D cells increases estrogen-dependent Src kinase and Erk1/2 MAP...