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IL8 — P2RY6

Text-mined interactions from Literome

Warny et al., J Biol Chem 2001 : Since lipopolysaccharide has been suggested to activate P2 receptors via nucleotide release, we tested whether IL-8 production stimulated by lipopolysaccharide might result from P2Y(6) activation ... Furthermore, IL-8 gene expression activated by lipopolysaccharide is enhanced by P2Y(6) overexpression and inhibited by P2Y(6) antisense oligonucleotides
Syeda et al., J Cell Physiol 2008 (MAP Kinase Signaling System) : Human neutrophil peptides ( HNP ) kill microorganisms but also modulate immune responses through upregulation of the chemokine IL-8 by activation of the nucleotide P2Y(6) receptor
Ben Yebdri et al., Eur J Immunol 2009 : Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is required for TLR1/2 induced neutrophil migration by regulating IL-8 secretion
Vieira et al., Am J Respir Crit Care Med 2011 (Airway Remodeling...) : In addition, selective activation of P2Y6 receptors induced the release of IL-6 and KC/IL-8 by murine and human lung epithelial cells in vitro
Uratsuji et al., J Immunol 2012 (Disease Models, Animal...) : Both P2Y(6)-specific antagonist and P2Y(6) antisense oligonucleotides significantly inhibited the production of IL-1a, IL-8/CXCL8 , and IL-6 by NHK