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IL17A — TGFB3

Text-mined interactions from Literome

Manel et al., Nat Immunol 2008 : In naive CD4+ T cells from mice, IL-17 is expressed in response to a combination of IL-6 or IL-21 and transforming growth factor-beta ( TGF-beta ) and requires induction of the nuclear receptor RORgammat
Gerosa et al., J Exp Med 2008 : Although IL-23, transforming growth factor beta , and IL-6 contained in the supernatants of activated mono-DCs played a role in the induction of IL-17 by human CD4 ( + ) T cells, IL-1beta, in combination with one or more of those factors, was required for IL-17 production, and its production determined the differential ability of the stimuli used to elicit mono-DCs to produce soluble factors directing IL-17 production
Kattah et al., Arthritis Rheum 2008 : T cell activation in the presence of recombinant IL-1beta, IL-6, and IL-23 reconstituted robust IL-17 production, and this was enhanced by transforming growth factor beta ( TGFbeta )