Gene interactions and pathways from curated databases and text-mining

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IL1A — SMN1

Text-mined interactions from Literome

Shephard et al., Am J Pathol 2004 : Conversely, adding exogenous IL-1alpha completely suppressed endogenous alpha-SMA induction
Wang et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2004 (Fibrosis) : IL-1alpha could induce the transdifferentiation of tubular epithelial myofibroblast, showing hypertrophy of cells elongated and fusiform shaped, with significantly enhanced expression of alpha-SMA and increased secretion of FN ( P < 0.05 )
Jin et al., Zhongguo Dang Dai Er Ke Za Zhi 2011 : Lentinan treatment inhibited up-regulation of the cell proliferation activity, a-SMA protein levels, FN, Col?and a-SMA mRNA expression induced by IL-1ß in a dose independent manner ( P < 0.01 )