Gene interactions and pathways from curated databases and text-mining

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STX1A — TNF

Text-mined interactions from Literome

Zhang et al., J Lab Clin Med 2001 (Escherichia coli Infections) : The results showed that anisodamine significantly suppressed Stx1 induced tumor necrosis factor-alpha (TNF-alpha) , interleukin-1beta (IL-1beta), and IL-8 production ... Reverse transcriptase-polymerase chain reaction ( RT-PCR ) showed that anisodamine suppressed Stx1 mediated TNF-alpha mRNA expression
Stricklett et al., J Infect Dis 2002 : TNF , both alone and in combination with IL-1, increased Stx-1 toxicity, Gb3 content, and Stx-1 binding
Lee et al., Infect Immun 2005 (Leukemia, Myeloid) : Here, we show that Stx1 induces apoptosis in the undifferentiated myelogenous leukemia cell line THP-1 in the absence of tumor necrosis factor alpha (TNF-alpha) or death receptor ( TNF receptor or Fas ) expression
Hughes et al., Kidney Int 1998 (Hemolytic-Uremic Syndrome) : Stx-1 greatly increased TNF release and mRNA levels while CHX, at concentrations that produced similar inhibition of protein synthesis, had no effect on TNF production