Gene interactions and pathways from curated databases and text-mining

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LTB — PGD

Text-mined interactions from Literome

Lin et al., Vet Immunol Immunopathol 2010 : The selective COX-2 NSAIDs carprofen ( Rimadyl ) and deracoxib ( Deramaxx ) inhibited PGD2 and PGE2 production but only slightly inhibited LTB4 and LTC4
Wheeldon et al., Br J Pharmacol 1993 : 2. Prostaglandin E2 ( PGE2 ) and PGD2 inhibited both OZ-induced LTB4 release ( EC50 0.72 microM and 0.91 microM respectively ), and FMLP induced O2- release ( EC50 0.42 microM and 0.50 microM respectively )