Gene interactions and pathways from curated databases and text-mining

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NQO2 — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Mirzayans et al., Carcinogenesis 1999 : We conclude that up-regulation of p53 by 4NQO is mediated solely by an ATM independent mechanism and that the p53 response is primarily triggered by persistent alkali-stable 4NQO-DNA adducts
Gong et al., Cancer Res 2007 (Liver Neoplasms, Experimental) : These results suggest that stress induced NQO1 and NQO2 transiently stabilize p53 , which leads to protection against adverse effects of stressors