Gene interactions and pathways from curated databases and text-mining

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INS — MSTN

Text-mined interactions from Literome

Barazzoni et al., Clin Nutr 2004 (Diabetes Mellitus, Experimental...) : In spite of opposite effects on muscle mass the potential role of basal circulating insulin in the regulation of myostatin expression is also undetermined
Chen et al., Biochem Biophys Res Commun 2009 (Diabetes Mellitus, Experimental...) : Upregulation of myostatin gene expression in streptozotocin induced type 1 diabetes mice is attenuated by insulin ... Furthermore, induction of myostatin expression could be attenuated by insulin in T1D mice
Guo et al., Diabetes 2012 (Diabetes Mellitus...) : MSTN inhibition in A-ZIP/F1 mice reduced blood glucose, serum insulin , triglyceride levels, and the rate of triglyceride synthesis, and improved insulin sensitivity