Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
FADD
→
TLR2
(increases, FADD Activity)
Aliprantis et al., EMBO J 2000* Evidence: Inhibition of the NF-kappaB pathway downstream of MyD88 potentiates apoptosis, indicating that these two pathways bifurcate at the level of MyD88. TLR2 signals for apoptosis through MyD88 via a pathway involving Fas-associated death domain protein (FADD) and caspase 8.