◀ Back to HMOX1

ETS2 — HMOX1

Text-mined interactions from Literome

Chung et al., J Biol Chem 2005 (Inflammation) : Role of Ets-2 in the regulation of heme oxygenase-1 by endotoxin ... Ets-1 and Ets-2 both induce HO-1 promoter activity ; however, Ets-2 was a more potent transactivator of HO-1 in macrophages ... To further delineate the role of Ets-2 in regulating HO-1 transcription, we performed HO-1 promoter analysis studies in macrophages ... Our data provide evidence that Ets-2 contributes to the up-regulation of HO-1 by the potent inflammatory stimulus LPS in macrophages
Chung et al., J Cell Physiol 2012 (Inflammation) : Transforming growth factor-ß1 suppression of endotoxin induced heme oxygenase-1 in macrophages involves activation of Smad2 and downregulation of Ets-2