Ganesh et al., Int Immunol 2009
(Thyroiditis, Autoimmune) :
Collectively, our results show that GM-CSF renders CD8a- DCs tolerogenic, and these DCs induce Foxp3+ and IL-10+ Tregs
Bhattacharya et al., J Leukoc Biol 2011
:
In our earlier work, we had shown that GM-CSF treatment of CBA/J mice can suppress ongoing thyroiditis by inducing tolerogenic CD8a ( - ) DCs, which helped expand and/or induce CD4 ( + ) Foxp3 ( + ) Tregs