Gene interactions and pathways from curated databases and text-mining

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PMPCB — TNF

Text-mined interactions from Literome

Nicholas et al., J Neurochem 2001 : Inhibition of tumour necrosis factor-alpha (TNFalpha) induced NF-kappaB p52 converts the metabolic effects of microglial derived TNFalpha on mouse cerebellar neurones to neurotoxicity
Zhang et al., Endocrinology 2007 : However, TNF induced a p52/RelB NFkappaB DNA binding complex in p50 null MEC nuclear extracts ... These data suggest that in wild-type MEC, TNF stimulates the interaction of bcl3 with p50 and p52 , and the binding of p52, as well as RelB, to cyclin D1 promoter kappaB sites, and as a consequence, stimulates the growth of MEC
Morello et al., J Immunol 2006 : IL-1beta and TNF-alpha rapidly activated p50 and p65, but not C-Rel, RelB, or p52 , and both IL-1beta- and TNF-alpha stimulated A2AR expression was inhibited by the IkappaB kinase 2 inhibitor AS602868 in a concentration dependent manner