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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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MPRIP — TNF

Text-mined interactions from Literome

Sun et al., J Biol Chem 1999 : RIP3 , however, attenuates both RIP and TNF receptor-1 induced NF-kappaB activation
Xie et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2006 : Immunofluorescence was used to determine the subcellular localization of RIP3 in NIH3T3 cell line and the effects of TNF-alpha and z-VAD.fmk on RIP3 for its localization changing
Irrinki et al., Mol Cell Biol 2011 (Necrosis) : FADD was found to mediate formation of the TNF-a induced pronecrotic RIP1-RIP3 kinase complex, whereas the I?B Kinase ( IKK ) subunit NEMO appears to function downstream of RIP1-RIP3
Chen et al., J Biol Chem 2013 (Necrosis) : We found that TNF induces Thr-231 and Ser-232 phosphorylation in mouse RIP3 (mRIP3) and this phosphorylation is required for mRIP3 to interact with mMLKL