Gene interactions and pathways from curated databases and text-mining

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BMP15 — GREM1

Text-mined interactions from Literome

Katoh et al., Int J Mol Med 2006 : GREM1 ( CKTSF1B1 ) inhibits BMP signaling through BMPR1A ( ALK3 ), BMPR1B ( ALK6 ) or ACVR1 ( ALK2 ) to SMAD1, SMAD5 or SMAD8
Tamminen et al., Oncogenesis 2013 : Here, we identify gremlin-1 , a known bone morphogenetic protein inhibitor crucial for embryonic development, as a potential therapeutic target for mesothelioma