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ANG — PI3

Text-mined interactions from Literome

Yang et al., J Neurosci 1999 (Hypertension) : Ang II stimulated PI3-kinase activity in both WKY and SHR brain neurons and was accompanied by its translocation from the cytoplasmic to the nuclear compartment
Kim et al., Circ Res 2000 : Ang1 induced phosphorylation of Tie2 and the p85 subunit of phosphatidylinositol 3'-kinase ( PI 3'-kinase ) and increased PI 3'-kinase activity in a dose dependent manner
Rocic et al., Am J Physiol Cell Physiol 2001 (Hypertrophy) : A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle
Gorin et al., FASEB J 2001 : Ang II causes rapid activation of Akt/PKB ( 5-10 min ) but delayed activation of phosphoinositide 3-kinase (PI3-K) ( 30 min )
Mochizuki et al., J Cell Sci 2002 : Phosphoinositide 3-kinase ( PI 3-kinase ) was activated by Ang2 through c-Fes and was involved in chemotaxis toward Ang2
Li et al., Am J Physiol Lung Cell Mol Physiol 2002 : ANG IV significantly increased upstream phosphatidylinositide (PI) 3-kinase ( PI3K ), PI-dependent kinase-1 (PDK-1), extracellular signal related kinases ( ERK1/2 ), and protein kinase B-alpha/Akt (PKB-alpha) activities, as well as downstream p70 ribosomal S6 kinase (p70S6K) activities and/or phosphorylation of these proteins
El Mabrouk et al., Am J Physiol Heart Circ Physiol 2004 (Hypertension) : We investigated whether phosphatidylinositol 3-kinase (PI3K) and 68-kDa Src associated during mitosis ( SAM68 ) are involved in angiotensin II (ANG II) growth signaling in vascular smooth muscle cells ( VSMCs ) from spontaneously hypertensive rats ( SHR )
Isenovic et al., Int J Mol Med 2004 : We have investigated the role of phosphatidylinositol 3-kinase (PI3K) and serine/threonine protein kinase B ( Akt ) in mediating vascular smooth muscle cells ( VSMC ) sodium pump ( Na+, K ( + ) -ATPase ) regulatory interactions between insulin-like growth factor-1 (IGF-1) and angiotensin II (Ang II)
Kanda et al., Cancer Res 2005 : Ang1 activated mitogen activated protein kinase ( MAPK ) and phosphoinositide 3-kinase (PI3K) in IBE cells and HUVECs
Tsigkos et al., J Cell Physiol 2006 : Regulation of Ang2 release by PTEN/PI3-kinase/Akt in lung microvascular endothelial cells ... Inhibition of PI3-kinase with wortmannin led to a stimulation of basal Ang2 release in EC, while overexpression of an active form of Akt reduced Ang2
Trouillon et al., Biochemistry 2010 : Angiogenin induces nitric oxide synthesis in endothelial cells through PI-3 and Akt kinases