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MAP3K4 — MAPK1
Text-mined interactions from Literome
Korchnak et al., Cell Signal 2009
:
Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase (
MAP3K ) that
activates multiple mitogen activated protein kinase (
MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
López-Pelaéz et al., Mol Biol Cell 2012
(Inflammation...) :
Cot/tpl2 is the only
MAP3K that
activates MKK1/2-Erk1/2 in Toll-like receptor activated macrophages
Warr et al., Dev Cell 2012
(Gonadal Dysgenesis, 46,XY...) :
Taken together, our data suggest a requirement for GADD45? in promoting
MAP3K4 mediated activation of p38
MAPK signaling in embryonic gonadal somatic cells for testis determination in the mouse