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ALOX5 — IL1B

Text-mined interactions from Literome

Bonizzi et al., Mol Cell Biol 1999 (Adenocarcinoma) : Reactive oxygen intermediate dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity
Hartman et al., Agents Actions 1993 (Hypersensitivity) : As previously reported, the 5-lipoxygenase/cyclooxygenase (5-LO/CO) inhibitor, SKF86002 ( 30 microM ), significantly inhibited both IL-1 beta and TNF-alpha release using either stimulus