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ADM — IL1B
Text-mined interactions from Literome
Udono et al., Invest Ophthalmol Vis Sci 2000
:
Regulation of the
ADM expression by basic fibroblast growth factor, interferon (IFN)-gamma, tumor necrosis factor-alpha, interleukin
(IL)1beta , or all-trans-retinoic acid was studied ... IFN-gamma and
IL-1beta induced
ADM expression in ARPE-19 cells
Görbig et al., J Hepatol 2001
(Calcium Signaling) :
ADM secretion was markedly
enhanced by tumour necrosis factor-alpha and
interleukin-1beta
Hofbauer et al., Hypertension 2002
:
For this purpose, we characterized the
effects of inflammatory cytokines, tumor necrosis factor-alpha ( 100 microg/L ),
interleukin-1beta ( 20 microg/L ), and interferon-gamma ( 0.5 U/L ) on
ADM gene expression in rat aortic vascular smooth muscle cells ( AVSMCs )
von der Hardt et al., Eur J Pharmacol 2002
:
The
effect of aerosolized
adrenomedullin on
interleukin-1 beta and transforming growth factor (TGF)-beta1 mRNA and protein expression was studied in surfactant depleted piglets, receiving aerosolized adrenomedullin ( adrenomedullin, n=6 ), aerosolized adrenomedullin plus i.v. N ( G ) -nitro-L-arginine-methylester ( adrenomedullin+L-NAME, n=5 ), or aerosolized saline solution ( control, n=6 )
Wong et al., Endocrinology 2005
(Inflammation) :
ADM increased initial secretion of MIF and
IL-1beta from both nonstimulated and LPS stimulated cells, and it also increased basal and LPS induced IL-6 secretion of the cells by 2- to 15-fold
Linscheid et al., Endocrinology 2005
(Sepsis) :
Interferon-gamma coadministration inhibited IL-1beta mediated ProCT and CGRP secretion by 78 and 34 %, respectively but augmented
IL-1beta mediated
ADM secretion by 50 %
Nishikimi et al., Cardiovasc Res 2005
:
( 2 )
IL-1beta significantly
increased gene expression of
adrenomedullin and its receptor components ( adrenomedullin : +46 %, CRLR : +460 %, RAMP2 : +32 %, RAMP3 : +350 %, all P < 0.01 )
Chini et al., Kidney Int 1997
:
MC grown in primary culture synthesized
ADM , and the synthesis was
stimulated by TNF alpha and
IL-1 beta but not by PDGF and EGF