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COPS5 — SMAD2

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: SMAD2 → COPS5 (increases, COPS5 Activity) Kim et al., Mol Cell Biol 2004*
  Evidence: Overexpression of Jab1/CSN5 increases Smad2 phosphorylation and enhances TGF-beta-induced transcriptional activity. The inhibition of endogenous Jab1/CSN5 expression by small interfering RNA (siRNA) induces Smad7 expression

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: SMAD2 — COPS5 Colland et al., Genome Res 2004
• IRef Bind_translation Interaction: SMAD2 — COPS5 (two hybrid) Colland et al., Genome Res 2004
• IRef Biogrid Interaction: COPS5 — SMAD2 (direct interaction, two hybrid) Colland et al., Genome Res 2004
• IRef Hprd Interaction: COPS5 — SMAD2 (two hybrid) Colland et al., Genome Res 2004
• IRef Intact Interaction: SMAD2 — COPS5 (physical association, two hybrid) Colland et al., Genome Res 2004
• IRef Ophid Interaction: SMAD2 — COPS5 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005