Gene interactions and pathways from curated databases and text-mining

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POLDIP2 — SRC

Text-mined interactions from Literome

Salinthone et al., Am J Physiol Gastrointest Liver Physiol 2004 (Inflammation) : Expression of IL-1beta, IL-6, IL-8, and COX-2 mRNA was reduced by 30 microM PP1, an Src family tyrosine kinase inhibitor, and by 25 microM SB-203580, a p38 MAPK inhibitor
Trevino et al., Cancer Res 2005 (Adenocarcinoma...) : Inhibition of c-Src activity resulted in decreased phosphorylation of Akt, p38 , and extracellular signal regulated kinase ( Erk ) -1/2
Scodelaro Bilbao et al., Arch Biochem Biophys 2010 : In this work, we studied the involvement of PKC and Src in the phosphorylation of ERK1/2, p38 and JNK1 MAPKs and in the modulation of ATF-1, c-Fos, c-Jun and Jun D transcription factors by ATP in MCF-7 breast cancer cells
Bhattacharjee et al., J Biol Chem 2011 (MAP Kinase Signaling System) : Our data show that Src kinase activity regulates IL-13 induced p38 MAPK tyrosine phosphorylation via the upstream kinases MKK3 or MKK6