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POU5F1 — WNT4
Text-mined interactions from Literome
Cole et al., Genes Dev 2008
:
Both Tcf3 depletion and
Wnt pathway activation cause
increased expression of
Oct4 , Nanog, and other pluripotency factors and produce ES cells that are refractory to differentiation
Marikawa et al., Stem Cells Dev 2011
:
Overexpression of
Oct4 was
sufficient to suppress
Wnt/ß-catenin signaling through its action as a transcriptional activator
Elizalde et al., Stem Cells 2011
:
Gene silencing of
Wnt-4 , but not Wnt-11,
reduced retinoic acid downregulation of
OCT4 and Nanog and upregulation of PAX6, ASCL1, HOXC5, and NEUROD1, suggesting that Wnt-4 promotes early neuronal differentiation
Li et al., Mol Cell Biochem 2012
(Adenomatous Polyposis Coli...) :
The purpose of this study was to determine whether
Oct4 was
regulated by
Wnt signaling in undifferentiated ES cells