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CD40LG — JUN
Text-mined interactions from Literome
Shen et al., J Immunol 2001
:
We demonstrate that
AP-1 ( Fos and Jun ),
induced transiently by
CD40 ligand or LPS, binds a DNA element in the mouse GL epsilon promoter
Dupoux et al., Blood 2009
:
This degradation is required for the macrophages to be fully functional as TRAF2 overexpression in differentiated cells decreases the
c-Jun N-terminal kinase mediated synthesis and the secretion of proinflammatory cytokines, such as interleukin-8 and monocyte chemoattractant protein 1 ( MCP-1 ) in
response to
CD40 ligand
Zhao et al., Invest Ophthalmol Vis Sci 2010
(Graves Ophthalmopathy...) :
CD40L induced the phosphorylation of p38 MAPK, extracellular regulated kinase1/2 ( ERK1/2 ),
c-Jun NH2-terminal kinase (JNK) , and IkappaB and the activation of NF-kappaB
Rau et al., Hepatology 2013
(Hepatitis C...) :
The antiviral effect of
CD40L required activation of
c-Jun N terminal kinases (JNK)1/2 , but not induction of apoptosis or the JAK/STAT pathway that is necessary for the antiviral effects of IFNs
Brenner et al., FEBS Lett 1997
:
Activation of T-lymphocytes via
gp39/CD40L induced a strong activation of
Jun-N-terminal kinase (JNK) and p38-K