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MAPK7 — NRG1
Text-mined interactions from Literome
Di Segni et al., J Mol Neurosci 2006
:
Taken together, these results indicate that in PC12-ErbB4 cells, the
NRG induced neuroprotective effect from MPP+ treatment, requires PI3K/PKB/Akt and
Ras/MapK signaling networks
Bernard et al., J Biol Chem 2012
(Disease Models, Animal...) :
Furthermore, in contrast to related ligands,
NRG4 enhanced cell survival but not proliferation or migration, and
stimulated phosphorylation of the anti-apoptotic mediator Akt but not ERK
MAPK
Kim et al., J Neurochem 2013
(MAP Kinase Signaling System) :
Stimulation of the ErbB receptors by
NRG1ß activated the phosphatidylinositol-3-kinase (PI3K) and
mitogen activated protein kinase ( MAPK )
Li et al., ASN neuro 2012
(Demyelinating Diseases) :
NRG1 activated
MAPK , induced c-Jun expression and promoted a loss of myelin segments in DRG explants isolated from both WT ( wild-type ) and Hsp70 KO ( knockout ) mice