Logarajah et al., Oncogene 2003
(Breast Neoplasms) :
When overexpressed in the nontransformed EpH4 mammary epithelial cell line, BCL-6 prevents the STAT-driven expression of the milk protein beta-casein and duct formation, and prevents apoptosis
Konnikova et al., BMC cancer 2003
(Astrocytoma) :
Moreover, STAT3 is required for the expression of the antiapoptotic genes survivin and Bcl-xL in the A172 glioblastoma cell line
Goetz et al., J Immunol 2005
:
Thus, STAT5 dependent bcl-x ( L ) up-regulation and enhanced B cell survival are not sufficient to drive the thymic B cell development observed in STAT5b-CA mice