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TP53 — UVRAG
Text-mined interactions from Literome
Dohn et al., Oncogene 2001
:
Furthermore, the differential
regulation of
p53 target genes by
p63alpha and DeltaNp63alpha suggests that p63 and p53 utilize both similar and different signaling pathways to execute their cellular functions
Harmes et al., Oncogene 2003
:
Positive and negative regulation of
deltaN-p63 promoter activity by p53 and deltaN-p63-alpha
contributes to differential regulation of
p53 target genes
Finlan et al., Cell cycle (Georgetown, Tex.) 2006
(Disease Progression) :
Given that
p63alphaDeltaN is
required for
p53 activation after DNA damage, we examined and found a high proportion of cells co-express p63alphaDeltaN and CK2 phosphorylated p53 after UV-irradiation
Khokhar et al., Cell Res 2008
:
Additionally, we observed a differential effect of p63 mutants on
wildtype-p63 mediated
induction of
p53/p63 and p63 specific target genes
Tucci et al., Proc Natl Acad Sci U S A 2012
(Neoplasm Metastasis...) :
p53 mutants
inhibit expression of both
p63 and miR-205, and the cell migration, in a cell line expressing endogenous mutated p53, can be abrogated by pre-miR-205 or silencing of mutated p53