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TP53 — TP53INP1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
TP53INP1
—
TP53
(direct interaction, pull down)
Tomasini et al., J Biol Chem 2003*
-
IRef Biogrid Interaction:
TP53INP1
—
TP53
(direct interaction, pull down)
Okamura et al., Mol Cell 2001*
-
IRef Biogrid Interaction:
TP53INP1
—
TP53
(physical association, affinity chromatography technology)
Tomasini et al., J Biol Chem 2003*
-
IRef Hprd Interaction:
TP53
—
TP53INP1
(in vitro)
Okamura et al., Mol Cell 2001*, Tomasini et al., J Biol Chem 2003*
-
IRef Ophid Interaction:
TP53INP1
—
TP53
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Okamura et al., Mol Cell 2001
:
Overexpression of
p53DINP1 and DNA damage by DSBs synergistically
enhanced Ser46 phosphorylation of
p53 , induction of p53AIP1 expression, and apoptotic cell death
Tomasini et al., J Biol Chem 2003
:
In agreement with these results we demonstrate that
TP53INP1s , in association with HIPK2,
regulate p53 transcriptional activity on p21, mdm2, pig3, and bax promoters
Tomasini et al., Oncogene 2005
(Acute Disease...) :
TP53INP1s also interact with the p53 gene and
regulate p53 transcriptional activity
Cano et al., Cancer Res 2009
(Lymphoma) :
Indeed,
TP53INP1 transcript induction on oxidative stress is strictly
dependent on
p53 ... Indeed,
TP53INP1 transcript induction on oxidative stress is strictly
dependent on
p53