Human Gene FAM171A1 (uc001iob.3) Description and Page Index
  Description: Homo sapiens family with sequence similarity 171, member A1 (FAM171A1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr10:15,253,644-15,413,058 Size: 159,415 Total Exon Count: 8 Strand: -
Coding Region
   Position: hg19 chr10:15,254,914-15,413,051 Size: 158,138 Coding Exon Count: 8 

Page IndexSequence and LinksUniProtKB CommentsGenetic AssociationsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:15,253,644-15,413,058)mRNA (may differ from genome)Protein (890 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMGI
neXtProtPubMedStanford SOURCETreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: F1711_HUMAN
DESCRIPTION: RecName: Full=Protein FAM171A1; AltName: Full=Astroprincin; Flags: Precursor;
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).
SIMILARITY: Belongs to the FAM171 family.

-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): FAM171A1
CDC HuGE Published Literature: FAM171A1
Positive Disease Associations: Hemoglobins
Related Studies:
  1. Hemoglobins
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 58.61 RPKM in Brain - Caudate (basal ganglia)
Total median expression: 754.69 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -365.291270-0.288 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018890 - Uncharacterised_FAM171

Pfam Domains:
PF10577 - Uncharacterised protein family UPF0560

ModBase Predicted Comparative 3D Structure on Q5VUB5
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
  Ensembl   
  Protein Sequence   
  Alignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AL050367 - Homo sapiens mRNA; cDNA DKFZp564A026 (from clone DKFZp564A026).
AY683003 - Homo sapiens astroprincin mRNA, complete cds.
BC109302 - Homo sapiens family with sequence similarity 171, member A1, mRNA (cDNA clone MGC:130014 IMAGE:40035211), complete cds.
BC109303 - Homo sapiens family with sequence similarity 171, member A1, mRNA (cDNA clone MGC:130015 IMAGE:40035213), complete cds.
BC034232 - Homo sapiens family with sequence similarity 171, member A1, mRNA (cDNA clone IMAGE:5276340), partial cds.
AK022946 - Homo sapiens cDNA FLJ12884 fis, clone NT2RP2003984, highly similar to Homo sapiens mRNA; cDNA DKFZp564A026 (from clone DKFZp564A026).
JD080476 - Sequence 61500 from Patent EP1572962.
JD394022 - Sequence 375046 from Patent EP1572962.
JD188923 - Sequence 169947 from Patent EP1572962.
JD354694 - Sequence 335718 from Patent EP1572962.
JD284480 - Sequence 265504 from Patent EP1572962.
JD336898 - Sequence 317922 from Patent EP1572962.
JD183708 - Sequence 164732 from Patent EP1572962.
JD339318 - Sequence 320342 from Patent EP1572962.
JD547694 - Sequence 528718 from Patent EP1572962.
JD468209 - Sequence 449233 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C10orf38, D3DRT9, F1711_HUMAN, NM_001010924, NP_001010924, Q32M49, Q5VUB5, Q8N4I0
UCSC ID: uc001iob.3
RefSeq Accession: NM_001010924
Protein: Q5VUB5 (aka F1711_HUMAN)
CCDS: CCDS31154.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001010924.1
exon count: 8CDS single in 3' UTR: no RNA size: 3964
ORF size: 2673CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 5449.00frame shift in genome: no % Coverage: 99.65
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.