Mouse Gene Tceanc (ENSMUST00000112188.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus transcription elongation factor A (SII) N-terminal and central domain containing (Tceanc), mRNA. (from RefSeq NM_001007577)
Gencode Transcript: ENSMUST00000112188.7
Gencode Gene: ENSMUSG00000051224.13
Transcript (Including UTRs)
   Position: mm10 chrX:166,499,812-166,510,478 Size: 10,667 Total Exon Count: 5 Strand: -
Coding Region
   Position: mm10 chrX:166,502,318-166,503,397 Size: 1,080 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:166,499,812-166,510,478)mRNA (may differ from genome)Protein (359 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: TEANC_MOUSE
DESCRIPTION: RecName: Full=Transcription elongation factor A N-terminal and central domain-containing protein; AltName: Full=TFIIS central domain-containing protein 1;
SIMILARITY: Contains 1 TFIIS central domain.
SIMILARITY: Contains 1 TFIIS N-terminal domain.
SEQUENCE CAUTION: Sequence=BC067008; Type=Frameshift; Positions=281;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -168.10464-0.362 Picture PostScript Text
3' UTR -670.902506-0.268 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR016492 - TF_IIS-rel
IPR003618 - TFIIS_cen_dom
IPR017923 - TFIIS_N

Pfam Domains:
PF07500 - Transcription factor S-II (TFIIS), central domain
PF08711 - TFIIS helical bundle-like domain

SCOP Domains:
47676 - Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
46942 - Elongation factor TFIIS domain 2
57783 - Zinc beta-ribbon
57903 - FYVE/PHD zinc finger

ModBase Predicted Comparative 3D Structure on Q3US16
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
 RGD    
 Protein Sequence    
 Alignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function

Biological Process:
GO:0006351 transcription, DNA-templated

Cellular Component:
GO:0005575 cellular_component
GO:0005634 nucleus


-  Descriptions from all associated GenBank mRNAs
  BC067008 - Mus musculus RIKEN cDNA A630018P17 gene, mRNA (cDNA clone IMAGE:6418163).
AK046546 - Mus musculus 4 days neonate male adipose cDNA, RIKEN full-length enriched library, clone:B430001P14 product:unclassifiable, full insert sequence.
AK140929 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130073L20 product:hypothetical Transcription elongation factor S-II, central region/Transcription factors TFIIS, elongin A, CRSP70, conserved containing protein, full insert sequence.
AK041519 - Mus musculus 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630018P17 product:hypothetical Conserved domain common to transcription factors TFIIS, elongin A, CRSP70/Elongation factor TFIIS domain 2 structure containing protein, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001007577, Q3US16, Q6NXL9, Q8BY92, TEANC_MOUSE, uc009uwv.1, uc009uwv.2
UCSC ID: uc009uwv.2
RefSeq Accession: NM_001007577
Protein: Q3US16 (aka TEANC_MOUSE)
CCDS: CCDS53249.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.