Mouse Gene Anks6 (ENSMUST00000084616.2) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default)
  Description: Mus musculus ankyrin repeat and sterile alpha motif domain containing 6 (Anks6), transcript variant 2, mRNA. (from RefSeq NM_001024136)
Gencode Transcript: ENSMUST00000084616.2
Gencode Gene: ENSMUSG00000066191.12
Transcript (Including UTRs)
   Position: mm10 chr4:47,015,689-47,057,306 Size: 41,618 Total Exon Count: 15 Strand: -
Coding Region
   Position: mm10 chr4:47,016,767-47,057,280 Size: 40,514 Coding Exon Count: 15 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:47,015,689-47,057,306)mRNA (may differ from genome)Protein (815 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsMGI
PubMedSOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: E9PUD3_MOUSE
DESCRIPTION: SubName: Full=Ankyrin repeat and SAM domain-containing protein 6;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -9.5026-0.365 Picture PostScript Text
3' UTR -417.501078-0.387 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom
IPR001660 - SAM
IPR013761 - SAM/pointed
IPR021129 - SAM_type1

Pfam Domains:
PF00023 - Ankyrin repeat
PF00536 - SAM domain (Sterile alpha motif)
PF07647 - SAM domain (Sterile alpha motif)
PF12796 - Ankyrin repeats (3 copies)
PF13606 - Ankyrin repeat
PF13637 - Ankyrin repeats (many copies)
PF13857 - Ankyrin repeats (many copies)

SCOP Domains:
140860 - Pseudo ankyrin repeat-like
47769 - SAM/Pointed domain
51735 - NAD(P)-binding Rossmann-fold domains
53613 - Ribokinase-like
53756 - UDP-Glycosyltransferase/glycogen phosphorylase
48403 - Ankyrin repeat

ModBase Predicted Comparative 3D Structure on E9PUD3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Descriptions from all associated GenBank mRNAs
  BC060663 - Mus musculus ankyrin repeat and sterile alpha motif domain containing 6, mRNA (cDNA clone IMAGE:30356260).
AK085318 - Mus musculus 0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630011C23 product:unclassifiable, full insert sequence.
AK008967 - Mus musculus adult male stomach cDNA, RIKEN full-length enriched library, clone:2210417J20 product:unclassifiable, full insert sequence.
BC072562 - Mus musculus ankyrin repeat and sterile alpha motif domain containing 6, mRNA (cDNA clone IMAGE:5707611), complete cds.
AK032990 - Mus musculus 12 days embryo male wolffian duct includes surrounding region cDNA, RIKEN full-length enriched library, clone:6720486H14 product:unclassifiable, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: E9PUD3, E9PUD3_MOUSE, NM_001024136, uc008sui.1
UCSC ID: uc008sui.1
RefSeq Accession: NM_001024136
Protein: E9PUD3 CCDS: CCDS18157.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.