The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF02861 - Clp amino terminal domain, pathogenicity island component PF14965 - Negative regulator of p53/TP53
ModBase Predicted Comparative 3D Structure on Q3UBX0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005244 voltage-gated ion channel activity GO:0005515 protein binding
Biological Process: GO:0006811 ion transport GO:0034220 ion transmembrane transport GO:0034765 regulation of ion transmembrane transport GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0060548 negative regulation of cell death GO:0071480 cellular response to gamma radiation