ID:RHAG_MOUSE DESCRIPTION: RecName: Full=Ammonium transporter Rh type A; AltName: Full=Erythrocyte membrane glycoprotein Rh50; AltName: Full=Rhesus blood group family type A glycoprotein; Short=Rh family type A glycoprotein; Short=Rh type A glycoprotein; AltName: CD_antigen=CD241; FUNCTION: May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane (By similarity). SUBUNIT: Heterotetramer (By similarity). SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (By similarity). SIMILARITY: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9QUT0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006873 cellular ion homeostasis GO:0015670 carbon dioxide transport GO:0015672 monovalent inorganic cation transport GO:0015695 organic cation transport GO:0015696 ammonium transport GO:0048821 erythrocyte development GO:0060586 multicellular organismal iron ion homeostasis GO:0072488 ammonium transmembrane transport
Protein Q9QUT0 (Reactome details) participates in the following event(s):
R-MMU-444416 RHAG transports NH4+ from cytosol to extracellular region (red blood cells) R-MMU-1237069 RhAG passively translocates carbon dioxide from the extracellular region to the cytosol R-MMU-1247645 RhAG passively translocates carbon dioxide from the cytosol to the extracellular region R-MMU-444411 Rhesus glycoproteins mediate ammonium transport. R-MMU-1237044 Erythrocytes take up carbon dioxide and release oxygen R-MMU-1247673 Erythrocytes take up oxygen and release carbon dioxide R-MMU-425366 Transport of bile salts and organic acids, metal ions and amine compounds R-MMU-425428 Amine compound SLC transporters R-MMU-1480926 O2/CO2 exchange in erythrocytes R-MMU-425407 SLC-mediated transmembrane transport R-MMU-382551 Transport of small molecules