Mouse Gene Triqk (ENSMUST00000183345.1) Description and Page Index
  Description: May play a role in cell growth and maintenance of cell morphology (By similarity). (from UniProt B2B9E1)
Gencode Transcript: ENSMUST00000183345.1
Gencode Gene: ENSMUSG00000055963.12
Transcript (Including UTRs)
   Position: mm10 chr4:12,906,858-12,983,553 Size: 76,696 Total Exon Count: 5 Strand: +
Coding Region
   Position: mm10 chr4:12,962,963-12,980,518 Size: 17,556 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsCTDRNA StructureProtein Structure
Other SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2019-09-20

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:12,906,858-12,983,553)mRNA (may differ from genome)Protein (86 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblExonPrimerGeneCardsMGIPubMed
Stanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: TRIQK_MOUSE
DESCRIPTION: RecName: Full=Triple QxxK/R motif-containing protein; AltName: Full=Triple repetitive-sequence of QXXK/R protein homolog;
FUNCTION: May play a role in cell growth and maintenance of cell morphology (By similarity).
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity).
TISSUE SPECIFICITY: Expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
DEVELOPMENTAL STAGE: Expressed in embryo from 7 to 17 dpc.
SIMILARITY: Belongs to the TRIQK family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene
  • C532162 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine
  • D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
  • D008627 Mercuric Chloride
  • D015215 Zidovudine
  • C088658 zoledronic acid

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -79.10249-0.318 Picture PostScript Text
3' UTR -749.703035-0.247 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR024842 - TRIQK

Pfam Domains:
PF15168 - Triple QxxK/R motif-containing protein family

ModBase Predicted Comparative 3D Structure on B2B9E1
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
GenBankRGDEnsembl   
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  DQ351292 - Mus musculus triqk mRNA, complete cds.
AK048604 - Mus musculus 16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130086A10 product:hypothetical protein, full insert sequence.
BC147183 - Mus musculus predicted gene, OTTMUSG00000004461, mRNA (cDNA clone MGC:182317 IMAGE:9056211), complete cds.
BC147184 - Mus musculus predicted gene, OTTMUSG00000004461, mRNA (cDNA clone MGC:182324 IMAGE:9056218), complete cds.
AK141699 - Mus musculus 9 days embryo whole body cDNA, RIKEN full-length enriched library, clone:D030030H21 product:unclassifiable, full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: B2B9E1, DQ351292, Gm11818, TRIQK_MOUSE, uc008sas.1, uc008sas.2, uc008sas.3
UCSC ID: uc008sas.3
RefSeq Accession: NM_173746
Protein: B2B9E1 (aka TRIQK_MOUSE)
CCDS: CCDS71348.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.