Description: Homo sapiens leucine zipper protein 4 (LUZP4), mRNA. RefSeq Summary (NM_016383): This gene encodes a leucine-zipper protein that was first defined as a cancer testis antigens. The encoded protein is an RNA binding protein that interacts with the mRNA export receptor nuclear RNA export factor 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]. Transcript (Including UTRs) Position: hg19 chrX:114,524,292-114,542,121 Size: 17,830 Total Exon Count: 4 Strand: + Coding Region Position: hg19 chrX:114,524,326-114,541,369 Size: 17,044 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q9P127
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary
AK093369 - Homo sapiens cDNA FLJ36050 fis, clone TESTI2018060, highly similar to Homo sapiens leucine zipper protein 4 (LUZP4), mRNA. AX748081 - Sequence 1606 from Patent EP1308459. AK314765 - Homo sapiens cDNA, FLJ95634, highly similar to Homo sapiens HOM-TES-85 tumor antigen (HOM-TES-85), mRNA. AF124430 - Homo sapiens HOM-TES-85 tumor antigen mRNA, complete cds. BC128134 - Homo sapiens leucine zipper protein 4, mRNA (cDNA clone MGC:149218 IMAGE:40112435), complete cds. BC128135 - Homo sapiens leucine zipper protein 4, mRNA (cDNA clone IMAGE:40112439), complete cds. JD337365 - Sequence 318389 from Patent EP1572962. JD500301 - Sequence 481325 from Patent EP1572962. JD092757 - Sequence 73781 from Patent EP1572962. JD530754 - Sequence 511778 from Patent EP1572962. JD225057 - Sequence 206081 from Patent EP1572962. JD202092 - Sequence 183116 from Patent EP1572962. JD350373 - Sequence 331397 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9P127 (Reactome details) participates in the following event(s):
R-HSA-8849157 TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally R-HSA-75096 Docking of the TAP:EJC Complex with the NPC R-HSA-72185 mRNA polyadenylation R-HSA-72180 Cleavage of mRNA at the 3'-end R-HSA-159101 NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) R-HSA-72187 mRNA 3'-end processing R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA R-HSA-72202 Transport of Mature Transcript to Cytoplasm R-HSA-109688 Cleavage of Growing Transcript in the Termination Region R-HSA-8953854 Metabolism of RNA R-HSA-73856 RNA Polymerase II Transcription Termination R-HSA-73857 RNA Polymerase II Transcription R-HSA-74160 Gene expression (Transcription)
US Server
