Description: Homo sapiens tetraspanin 16 (TSPAN16), mRNA. RefSeq Summary (NM_012466): The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein might couple to signal transduction pathways and possibly modulate cellular activation and adhesion in haemopoietic and neural tissue. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]. Transcript (Including UTRs) Position: hg19 chr19:11,406,824-11,437,672 Size: 30,849 Total Exon Count: 7 Strand: + Coding Region Position: hg19 chr19:11,406,974-11,437,520 Size: 30,547 Coding Exon Count: 7
ID:TSN16_HUMAN DESCRIPTION: RecName: Full=Tetraspanin-16; Short=Tspan-16; AltName: Full=Tetraspanin TM4-B; AltName: Full=Transmembrane 4 superfamily member 16; SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Probable). TISSUE SPECIFICITY: Broadly expressed in most human tissues and cell lines including neural and bone marrow derived tissues. SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UKR8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Gene Ontology (GO) Annotations with Structured Vocabulary
US Server
