Human Gene ZNF155 (uc010xwt.2)
  Description: Homo sapiens zinc finger protein 155 (ZNF155), transcript variant 5, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:44,488,322-44,502,477 Size: 14,156 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr19:44,494,217-44,501,626 Size: 7,410 Coding Exon Count: 4 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:44,488,322-44,502,477)mRNA (may differ from genome)Protein (549 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsH-INV
HGNCLynxMGIOMIMPubMedUniProtKB
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: J3KQ08_HUMAN
DESCRIPTION: SubName: Full=Zinc finger protein 155;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.39 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 128.70 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -61.60217-0.284 Picture PostScript Text
3' UTR -249.44851-0.293 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001909 - Krueppel-associated_box
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd

Pfam Domains:
PF00096 - Zinc finger, C2H2 type
PF01352 - KRAB box
PF12874 - Zinc-finger of C2H2 type
PF13894 - C2H2-type zinc finger
PF13912 - C2H2-type zinc finger

SCOP Domains:
48695 - Multiheme cytochromes
109640 - KRAB domain (Kruppel-associated box, Pfam 01352)
57667 - C2H2 and C2HC zinc fingers

ModBase Predicted Comparative 3D Structure on J3KQ08
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK314510 - Homo sapiens cDNA, FLJ95328, highly similar to Homo sapiens zinc finger protein 155 (pHZ-96) (ZNF155), mRNA.
AK297384 - Homo sapiens cDNA FLJ51246 complete cds.
AK297360 - Homo sapiens cDNA FLJ51668 complete cds, highly similar to Zinc finger protein 155.
AK022875 - Homo sapiens cDNA FLJ12813 fis, clone NT2RP2002503, weakly similar to ZINC FINGER PROTEIN 45.
AF187986 - Homo sapiens zinc finger protein ZNF155 mRNA, complete cds.
BC126377 - Homo sapiens zinc finger protein 155, mRNA (cDNA clone MGC:161655 IMAGE:8992093), complete cds.
BC130381 - Homo sapiens zinc finger protein 155, mRNA (cDNA clone MGC:163253 IMAGE:40146412), complete cds.
BC075050 - Homo sapiens zinc finger protein 155, mRNA (cDNA clone MGC:104125 IMAGE:30915579), complete cds.
BC075051 - Homo sapiens zinc finger protein 155, mRNA (cDNA clone MGC:103962 IMAGE:30915363), complete cds.
EU446918 - Synthetic construct Homo sapiens clone IMAGE:100069960; IMAGE:100012127; FLH257053.01L zinc finger protein 155 (ZNF155) gene, encodes complete protein.
KJ897773 - Synthetic construct Homo sapiens clone ccsbBroadEn_07167 ZNF155 gene, encodes complete protein.
JD044471 - Sequence 25495 from Patent EP1572962.
JD075081 - Sequence 56105 from Patent EP1572962.
U09852 - Human zinc finger protein (ZNF155) mRNA, partial cds.

-  Other Names for This Gene
  Alternate Gene Symbols: J3KQ08, J3KQ08_HUMAN, NM_001260488, NP_001247417, uc010xwt.1
UCSC ID: uc010xwt.2
RefSeq Accession: NM_001260488
Protein: J3KQ08 CCDS: CCDS58668.1, CCDS12634.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001260488.1
exon count: 6CDS single in 3' UTR: no RNA size: 2718
ORF size: 1650CDS single in intron: no Alignment % ID: 99.93
txCdsPredict score: 3444.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.