Human Gene VSIG10L (uc002pwf.3) Description and Page Index
  Description: Homo sapiens V-set and immunoglobulin domain containing 10 like (VSIG10L), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:51,834,795-51,845,378 Size: 10,584 Total Exon Count: 10 Strand: -
Coding Region
   Position: hg19 chr19:51,835,865-51,845,378 Size: 9,514 Coding Exon Count: 10 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
Genomic Sequence (chr19:51,834,795-51,845,378)mRNA (may differ from genome)Protein (867 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsHGNC
LynxMGIneXtProtOMIMPubMedStanford SOURCE

-  Comments and Description Text from UniProtKB
DESCRIPTION: RecName: Full=V-set and immunoglobulin domain-containing protein 10-like; Flags: Precursor;
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential).
SIMILARITY: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 79.98 RPKM in Esophagus - Mucosa
Total median expression: 198.07 RPKM

View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -320.511070-0.300 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007110 - Ig-like
IPR013783 - Ig-like_fold
IPR003599 - Ig_sub
IPR003598 - Ig_sub2

Pfam Domains:
PF00047 - Immunoglobulin domain
PF13895 - Immunoglobulin domain
PF13927 - Immunoglobulin domain

SCOP Domains:
48726 - Immunoglobulin

ModBase Predicted Comparative 3D Structure on Q86VR7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
  Protein Sequence   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016020 membrane
GO:0016021 integral component of membrane

-  Descriptions from all associated GenBank mRNAs
  BC032383 - Homo sapiens, similar to collagen, clone IMAGE:5179937, mRNA.
AF086436 - Homo sapiens full length insert cDNA clone ZD80E03.
JD063516 - Sequence 44540 from Patent EP1572962.
JD301022 - Sequence 282046 from Patent EP1572962.
JD265365 - Sequence 246389 from Patent EP1572962.
JD047038 - Sequence 28062 from Patent EP1572962.
JD068612 - Sequence 49636 from Patent EP1572962.
BC016993 - Homo sapiens, clone IMAGE:4401841, mRNA.
BC049212 - Homo sapiens hypothetical protein LOC147645, mRNA (cDNA clone IMAGE:5241034), partial cds.
JD519971 - Sequence 500995 from Patent EP1572962.
JD252715 - Sequence 233739 from Patent EP1572962.
JD331410 - Sequence 312434 from Patent EP1572962.
JD174141 - Sequence 155165 from Patent EP1572962.
JD392452 - Sequence 373476 from Patent EP1572962.
JD097551 - Sequence 78575 from Patent EP1572962.
JD327645 - Sequence 308669 from Patent EP1572962.
JD138677 - Sequence 119701 from Patent EP1572962.
JD559556 - Sequence 540580 from Patent EP1572962.
JD068048 - Sequence 49072 from Patent EP1572962.
JD564885 - Sequence 545909 from Patent EP1572962.
JD281219 - Sequence 262243 from Patent EP1572962.
JD392178 - Sequence 373202 from Patent EP1572962.
JD565705 - Sequence 546729 from Patent EP1572962.
BC131493 - Homo sapiens cDNA clone IMAGE:40076783, partial cds.
JD371027 - Sequence 352051 from Patent EP1572962.
JD212157 - Sequence 193181 from Patent EP1572962.
JD225598 - Sequence 206622 from Patent EP1572962.
JD239410 - Sequence 220434 from Patent EP1572962.
JD412204 - Sequence 393228 from Patent EP1572962.
JD392259 - Sequence 373283 from Patent EP1572962.
JD526523 - Sequence 507547 from Patent EP1572962.
JD075218 - Sequence 56242 from Patent EP1572962.
JD106982 - Sequence 88006 from Patent EP1572962.
JD276712 - Sequence 257736 from Patent EP1572962.
JD148854 - Sequence 129878 from Patent EP1572962.
JD307998 - Sequence 289022 from Patent EP1572962.
JD375037 - Sequence 356061 from Patent EP1572962.
JD472139 - Sequence 453163 from Patent EP1572962.
JD481327 - Sequence 462351 from Patent EP1572962.
JD483516 - Sequence 464540 from Patent EP1572962.
JD294628 - Sequence 275652 from Patent EP1572962.
JD234743 - Sequence 215767 from Patent EP1572962.
JD489971 - Sequence 470995 from Patent EP1572962.
JD142730 - Sequence 123754 from Patent EP1572962.
JD058073 - Sequence 39097 from Patent EP1572962.
JD271799 - Sequence 252823 from Patent EP1572962.
JD406819 - Sequence 387843 from Patent EP1572962.
JD417332 - Sequence 398356 from Patent EP1572962.
JD055062 - Sequence 36086 from Patent EP1572962.
JD125006 - Sequence 106030 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001163922, NP_001157394, Q86VR7, VS10L_HUMAN
UCSC ID: uc002pwf.3
RefSeq Accession: NM_001163922
Protein: Q86VR7 (aka VS10L_HUMAN)
CCDS: CCDS54300.1

-  Gene Model Information
category: coding nonsense-mediated-decay: no RNA accession: NM_001163922.1
exon count: 10CDS single in 3' UTR: no RNA size: 3674
ORF size: 2604CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 5405.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.