Human Gene TEX33 (uc003aqf.3)
  Description: Homo sapiens testis expressed 33 (TEX33), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr22:37,387,160-37,403,877 Size: 16,718 Total Exon Count: 6 Strand: -
Coding Region
   Position: hg19 chr22:37,387,220-37,400,028 Size: 12,809 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr22:37,387,160-37,403,877)mRNA (may differ from genome)Protein (280 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
H-INVHGNCHPRDLynxMGIneXtProt
PubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: TEX33_HUMAN
DESCRIPTION: RecName: Full=Testis-expressed sequence 33 protein;
SEQUENCE CAUTION: Sequence=CAA72029.1; Type=Erroneous gene model prediction;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 75.83 RPKM in Testis
Total median expression: 75.87 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -51.70146-0.354 Picture PostScript Text
3' UTR -8.9260-0.149 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF15400 - Testis-expressed sequence 33 protein family

ModBase Predicted Comparative 3D Structure on O43247
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC042635 - Homo sapiens chromosome 22 open reading frame 33, mRNA (cDNA clone MGC:35206 IMAGE:5171722), complete cds.
CR456416 - Homo sapiens cE81G9.2 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.cE81G9.2).
CU012977 - Homo sapiens cE81G9.C22.2, mRNA (cDNA clone IMAGE:100000138), complete cds, with stop codon, in Gateway system.
KJ896068 - Synthetic construct Homo sapiens clone ccsbBroadEn_05462 TEX33 gene, encodes complete protein.
AB528089 - Synthetic construct DNA, clone: pF1KE0492, Homo sapiens EAN57 gene for Protein EAN57, without stop codon, in Flexi system.
CU013265 - Homo sapiens cE81G9.C22.2, mRNA (cDNA clone IMAGE:100000042), complete cds, without stop codon, in Gateway system.
JD215870 - Sequence 196894 from Patent EP1572962.
JD042531 - Sequence 23555 from Patent EP1572962.
JD203721 - Sequence 184745 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B1AH46, C22orf33, EAN57, NM_001163857, NP_848647, O43247, Q6ICF2, Q8IVQ2, Q9Y4V8, TEX33_HUMAN
UCSC ID: uc003aqf.3
RefSeq Accession: NM_001163857
Protein: O43247 (aka TEX33_HUMAN)
CCDS: CCDS54524.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001163857.1
exon count: 6CDS single in 3' UTR: no RNA size: 1049
ORF size: 843CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1780.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.