The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O75937
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AF161449 - Homo sapiens HSPC331 mRNA, partial cds. AF161433 - Homo sapiens HSPC315 mRNA, partial cds. BC033159 - Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 8, mRNA (cDNA clone MGC:45787 IMAGE:4330676), complete cds. AF083190 - Homo sapiens SPF31 (SPF31) mRNA, complete cds. BX538122 - Homo sapiens mRNA; cDNA DKFZp686P08160 (from clone DKFZp686P08160). JD377546 - Sequence 358570 from Patent EP1572962. JD454939 - Sequence 435963 from Patent EP1572962. JD271151 - Sequence 252175 from Patent EP1572962. JD203190 - Sequence 184214 from Patent EP1572962. JD043041 - Sequence 24065 from Patent EP1572962. JD289226 - Sequence 270250 from Patent EP1572962. AK300797 - Homo sapiens cDNA FLJ61418 complete cds, highly similar to DnaJ homolog subfamily C member 8. JD121389 - Sequence 102413 from Patent EP1572962. JD252010 - Sequence 233034 from Patent EP1572962. JD259825 - Sequence 240849 from Patent EP1572962. JD189370 - Sequence 170394 from Patent EP1572962. JD288879 - Sequence 269903 from Patent EP1572962. JD390949 - Sequence 371973 from Patent EP1572962. JD392905 - Sequence 373929 from Patent EP1572962. JD554856 - Sequence 535880 from Patent EP1572962. JD102498 - Sequence 83522 from Patent EP1572962. JD381133 - Sequence 362157 from Patent EP1572962. JD230510 - Sequence 211534 from Patent EP1572962. JD180990 - Sequence 162014 from Patent EP1572962. KJ898410 - Synthetic construct Homo sapiens clone ccsbBroadEn_07804 DNAJC8 gene, encodes complete protein. CR456900 - Homo sapiens full open reading frame cDNA clone RZPDo834B047D for gene DNAJC8, DnaJ (Hsp40) homolog, subfamily C, member 8; complete cds, incl. stopcodon.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein O75937 (Reactome details) participates in the following event(s):
R-HSA-72124 Formation of the Spliceosomal A Complex R-HSA-72143 Lariat Formation and 5'-Splice Site Cleavage R-HSA-72139 Formation of the active Spliceosomal C (B*) complex R-HSA-72127 Formation of the Spliceosomal B Complex R-HSA-72130 Formation of an intermediate Spliceosomal C (Bact) complex R-HSA-156661 Formation of Exon Junction Complex R-HSA-72163 mRNA Splicing - Major Pathway R-HSA-72172 mRNA Splicing R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA R-HSA-8953854 Metabolism of RNA
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